If Cenforce Professional contains sildenafil, it can interact with blood-pressure medicines. It is not automatically unsafe, but it can lower blood pressure further. Official sildenafil information recommends caution with antihypertensives and especially with alpha-blockers. D DailyMed +1 Amlodipine: has been studied with sildenafil; additional BP lowering occurred, so monitoring is sensible. D DailyMed Alpha-blockers such as tamsulosin or doxazosin: greater risk of dizziness, light-headedness, or fainting; sildenafil is generally started at a lower dose when used with these. D DailyMed Nitrates such as nitroglycerin/GTN or isosorbide: do not use sildenafil with these because the combination can cause a dangerous fall in blood pressure. D DailyMed If you tell me the exact blood-pressure medicine and dose you're taking (for example, amlodipine 5 mg, telmisartan 40 mg, or tamsulosin 0.4 mg), I can check that specific combination.