Avana 100 mg (which contains avanafil) should be stored away from heat at all times, not only after opening or at specific times. General storage recommendations include: Store at room temperature, typically 20–25°C (68–77°F), unless the product label specifies otherwise. Keep it away from excessive heat, direct sunlight, and moisture. Store it in its original packaging until you're ready to take a dose, to help protect it from light and humidity. Avoid keeping it in places that can become hot or humid, such as a car, bathroom, or near a stove. Keep it out of the reach of children and pets. Proper storage helps maintain the medication's stability and effectiveness until its expiration date. If tablets have been exposed to extreme heat (for example, left in a very hot car for an extended period), it's a good idea to ask a pharmacist whether they should be replaced.