If Cenforce 130 contains sildenafil, then any dose of it can interact dangerously with nitrate medicines. The interaction isn't specific to a particular Cenforce strength: sildenafil can greatly increase the blood-pressure-lowering effect of nitrates. D DailyMed +1 Examples of nitrates include: Nitroglycerin / glyceryl trinitrate (GTN) — tablets, sprays or patches Isosorbide mononitrate Isosorbide dinitrate Recreational “poppers” containing nitrites Do not take Cenforce/sildenafil if you use these medicines. If you've already taken sildenafil and then develop chest pain, tell emergency medical staff that you took sildenafil and do not take nitroglycerin yourself unless a clinician specifically directs you. The safe timing for giving nitrates after sildenafil isn't established in the prescribing information. D DailyMed Also, 130 mg is above the standard maximum recommended sildenafil dose of 100 mg for ED. D DailyMed If you tell me the exact nitrate medicine and dose you're taking, I can explain the interaction specifically.