Tadalista can be dangerous in overdose, because it contains tadalafil, a PDE5 inhibitor. Taking more than the prescribed dose increases the risk of serious side effects, some of which can be life-threatening. Here’s a detailed breakdown  Risks of Tadalista Overdose Severe hypotension (low blood pressure): PDE5 inhibitors widen blood vessels. In overdose, this can dramatically lower blood pressure, leading to dizziness, fainting, or shock. Especially dangerous if combined with nitrates (like nitroglycerin) or certain blood pressure medications. Prolonged erection (priapism): Overdose increases the risk of an erection lasting more than 4 hours, which can cause permanent penile tissue damage if untreated. Cardiovascular risks: Increased heart rate, palpitations, or chest pain may occur. People with heart disease are at higher risk of heart attack or arrhythmia. Other side effects (more severe or frequent): Headache, flushing, dizziness, vision or hearing disturbances, nausea, back/muscle pain. Severe overdose may cause confusion or fainting.   Safe Use Guidelines Stick to prescribed dose: Tadalafil doses usually range from 2.5 mg to 20 mg for on-demand use or daily use. Do not take more than one dose in 24 hours. Avoid combination with nitrates or excessive alcohol. Seek immediate medical help if: You have an erection lasting >4 hours Chest pain, shortness of breath, or sudden dizziness occurs Severe vision or hearing changes