Fildena CT 100, which contains sildenafil citrate (the same active ingredient as Viagra), can be used by men with liver issues, but caution is required. If you have liver problems, particularly severe liver impairment, you should consult a healthcare provider before using this medication. How Liver Issues Affect the Use of Fildena CT 100: Metabolism of Sildenafil: Sildenafil is metabolized in the liver, primarily by enzymes such as CYP3A4 and CYP2C9. In individuals with liver impairment, the liver may not process the medication as efficiently, leading to higher levels of sildenafil in the bloodstream, which can increase the risk of side effects. Reduced Dosage for Liver Impairment: In patients with mild to moderate liver impairment, your doctor may recommend starting with a lower dose of Fildena CT 100, such as 25 mg or 50 mg, and carefully monitoring for side effects. This is because the drug may stay in your system longer, potentially leading to increased side effects like headaches, flushing, dizziness, or more serious reactions. Severe Liver Issues: If you have severe liver problems (such as cirrhosis or hepatitis), it is generally not recommended to use Fildena CT 100 or any PDE5 inhibitors like sildenafil. This is because the liver cannot effectively clear the medication, increasing the risk of harmful side effects. In such cases, your healthcare provider might explore other treatments for erectile dysfunction that do not involve sildenafil.