Poxet 60 mg should not be taken twice a day. Here’s a detailed explanation: Why twice-daily dosing is unsafe Maximum recommended frequency Dapoxetine (Poxet) is a short-acting SSRI specifically designed for on-demand use. Approved dosing: 1 tablet 1–3 hours before ***** activity, no more than once every 24 hours. Risk of side effects Taking it twice a day can cause: Severe nausea, vomiting, dizziness Fainting or low blood pressure Heart palpitations or arrhythmias in sensitive individuals Increased risk of serotonin syndrome (dangerous overactivation of serotonin in the brain) Dapoxetine is not for daily use Unlike other SSRIs for depression, Poxet is short-acting and meant for occasional use, not chronic daily dosing. Repeated dosing within 24 hours doesn’t increase effectiveness but dramatically increases risk. Safe use guidelines Take 1 tablet 1–3 hours before ***** activity. Do not exceed 60 mg in 24 hours. Avoid alcohol or other serotonergic drugs without consulting a doctor. If the current dose is ineffective, consult a doctor—never increase frequency yourself. If you want, I can make a quick table showing all Poxet doses (30 mg, 60 mg, 90 mg) and their safe usage limits, which makes it super easy to see what’s safe and what’s risky. This is very helpful for avoiding overdose or side effects.