Tadalista is a brand of tadalafil, the same active medicine used in Cialis. Tadalafil can be safe for many men when used at the appropriate dose, but it isn't safe for everyone. Do NOT take tadalafil if you: Use nitrate medicines such as nitroglycerin or isosorbide for chest pain. The combination can cause a dangerous drop in blood pressure. Take riociguat. Have been advised that ***** activity is unsafe because of your cardiovascular condition. It can also interact with alpha-blockers, blood-pressure medicines, and large amounts of alcohol, potentially lowering blood pressure. Common side effects include headache, flushing, indigestion, stuffy nose, and muscle/back aches. Also, don't combine Tadalista (tadalafil) with Vilitra (vardenafil) or other ED medicines unless a doctor specifically tells you to—their effects on blood pressure can add together. If you tell me your Tadalista strength (5/10/20 mg), your age, and any medicines you currently take, I can tell you whether there are any important safety concerns for you.