Vidalista Professional contains tadalafil, a medicine from the PDE-5 inhibitor group. It is generally used for erectile dysfunction (ED) in adult men and should be used only when it is medically appropriate for the person taking it. It can usually be used safely in situations such as: Adult men with erectile dysfunction who have been evaluated and advised that tadalafil is suitable. ***** activity with adequate arousal, because the medicine helps improve blood flow but does not create an erection without ***** stimulation. At the prescribed dose and timing (many Vidalista Professional products contain tadalafil 20 mg; follow the instructions from a healthcare professional rather than adjusting the dose yourself). It should not be used or should be checked with a doctor first if you: Take nitrate medicines for chest pain/heart problems (such as nitroglycerin), because the combination can cause a dangerous drop in blood pressure. Take certain medicines such as riociguat or have certain serious heart conditions. Have had a recent heart attack, stroke, severe heart disease, or symptoms such as chest pain during ***** activity. Have significant kidney or liver problems unless a clinician has reviewed your dose. Seek urgent medical help if you develop chest pain, severe dizziness/fainting, sudden vision or hearing changes, or an erection lasting more than 4 hours. If you tell me your age, any heart/BP medicines you take, and whether you mean “safe place to use” (country/legal availability) or “safe situation to take it,” I can tailor the answer.